BDBM50506714 CHEMBL4553054

SMILES O\N=C1\c2ccccc2-c2nc3ccc(cc3nc12)C(O)=O

InChI Key InChIKey=PYABQVKREKYNJT-RGEXLXHISA-N

Data  2 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506714   

TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506714(CHEMBL4553054)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of JNK in human THP1-Blue cells assessed as reduction in LPS-induced NFkappaB/AP1 activation preincubated for 30 mins followed by LPS-stim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506714(CHEMBL4553054)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production preincubated for 30 mins followed by LPS-stimulation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed